McDonald Kriterleri (2017 Revizyonu)

Klinik atak sayısı

“Clinical attack” = monophasic clinical episode with patient-reported symptoms and objective findings reflecting inflammatory demyelinating CNS event (focal or multifocal), subacute or acute, for ≥24 hrs, with or without recovery, and no fever or infection present; attack, relapse, exacerbation, and clinically isolated syndrome (first episode) are all synonymous

Objektif klinik kanıtı olan lezyon sayısı

“Objective clinical evidence” = abnormality on neurologic exam, imaging (MRI or optical coherence tomography), or visual evoked potentials, corresponding to anatomical location suggested by symptoms

Farklı anatomik lokalizasyonda lezyon içeren önceki atak kanıtı

Farklı MSS bölgesinde ek klinik atak veya MRI ile mekanda yayılım